Overlapping of CK7 and HOXB4 with some Histopathological Variables in Ovarian Cancer Patients

Nuha Alaa Hamza, Kareem Hamed Ghali, Hameed Naeem Mousa

Abstract: Ovarian carcinoma (OC) is one of commonest cancers ranks 7 th in both incidence and mortality among women worldwide. The study included fifty three samples of ovarian tumor patients, twenty eight of them were malignancy and twenty five were benign. Those patients' samples then compared with twenty three of non - cancer tissues samples as control group. This study was carried out in Laboratories of the College of Science/ Department of Biology, Wasit University, during period between 1 November 2017 to 1 November 2018 .The study of CK7 and HOXB4 genes e xpression was done by immunohistochemistry (IHC) technique. The results showed significant c orrelation between CK7 and HOXB4 in OC. O verlapping effects of histopathological variables in ovarian cancer patients with CK7 expression, showed no significant (p > 0.05) correlation coefficient between OC and histopathological variables (stage, grade and type) in related to CK7 expression . HOXB4 show ed significant (p

Keywords: Cancer , ovarian, CK7, HOXB4 , Correlation , Overlapping