A Study Based on Indian Population on Risk Assessment and Comorbid Conditions in Sudden Unexpected Death in Epilepsy (SUDEP)

Sujithra Srinivas, Varsha Priyadarshini .R

Abstract: Sudden unexpected death in epilepsy (SUDEP) as considerable death rates, which is caused by a neurological disorder. However the recent advancement in technology and medicine has improved diagnosis and treatments in seizures and epilepsy control .Commercial available Anti epilepsy drugs (AED) are proven to have control over the conditions at a higher rate. Although with more efficient AED and diagnosis the sudden unexpected death in epilepsy (SUDEP) causes still remain highly unpredictable. The mortality rate of SUDEP is reasonably scattered in a broader spectrum which accounts to most inconclusive deaths which is not found under autopsy or toxicology study. The inconclusive nature of sudden unexpected death in epilepsy (SUDEP) has led to investigation of occurrences of the event and preventive measures for this fatal scenario which can lead to declination of early death in epilepsy. In this short review, we compile evidence from epidemiological research of 70 sudden unexpected death in epilepsy (SUDEP) cases, which can help an individual assess the personal risk of SUDEP. Besides varying global practices and health care policy, health care providers are looking forward to promote routine SUDEP awareness in patient counselling. Detailed understanding of the risk may improve the patient adherence to the disease, treatments and optimization of the death.

Keywords: Sudden unexpected death in epilepsy (SUDEP), neurological disorder, risk assessment, comorbid conditions