Risk of Ovarian Cancer Compare to benign Ovarian Disease among Women in Indian Scenario

Dr. Sambhunath Bandyopadhyay, Sudipta Banerjee, Dr. Sunit K. Mukhopadhayay, Dr. Debarshi Jana

Abstract: Introduction: Ovarian cancer is one of the most common cancers of women in India. This study aimed to find out the risks such as age, menopausal status, age at menopause, age at menarche, parity, age at first pregnancy, use of oral contraceptives, domicile status, literacy, occupation and BMI of ovarian in comparison with benign ovarian diseases in females. Methods: In this study 100 ovarian cancer patients and 100 women with benign ovarian diseases, who attended at Out Patient Door (OPD) of IPGME&R and SSKM Hospital, Kolkata, India during the period from January, 2010 to December, 2016 were included. Results: Significant risk of ovarian cancer was found in women who attained menopause after 55 years of age (OR-17.60), early menarche (OR-4.76), late menarche (OR-3.35), unmarried (OR-5.26), nulliparous (OR-7.10), late age at first pregnancy (OR-8.30) and related to the occupation (OR-0.44). No increased risk was found in OCP users (OR- 0.36) and occupation (OR-0.44). Patients with a high BMI were at a higher risk (OR-6.65). Discussion: Several risk factors which had already been established by researchers. But the studies were based on different populations of different geographical areas. This study is based on the females of eastern India. Thus the risk factors established through this study may help for early detection and prevention of ovarian cancer in this region.

Keywords: Cancer, ovarian cancer, benign ovarian disease, risk factors, India