Is Intraoperative Radiofrequency Ablation a Therapeutic Alternative for Solitary Pancreatic Insulinoma of Difficult Position? A Clinical Case Report

Mitra Dipankar S

Abstract: Insulinomas are most common functioning neuroendocrine tumors of the pancreas. The great majority (>90%) of insulinomas are benign and can be surgically cured. We describe a patient with benign insulinoma with symptoms of neuroglycopenia with raised serum insulin and C peptide levels. Preoperative computerized tomogram scan (CT) had confirmed aninsulinomain the uncinate process close to superior mesenteric vein (SMV). Initial plan of enucleation of the mass had been changed to successful use of radiofrequency ablation (RFA), after considering possible high morbidity of Whipple?s procedure and enucleationhadnot being a possible option, technically. During the16 - week follow - up, the patient had found to becured as episodes of hypoglycemia had been absent and a control CT, 4 weeks after RFA, did not revealany residual tumor.

Keywords: Insulinoma, Pancreatic neuroendocrine tumor, Radiofrequency Ablation