Gingival Crevicular Fluid (GCF): A Diagnostic Tool for the Detection of Periodontal Health and Diseases: A Review

Dr. Himanshi Sharma, Dr. Nitin Tomar, Dr. Mohd Nazar Rana, Dr. Mayur Kaushik

Abstract: GCF (Gingival Crevicular Fluid) is the fluid found in gingival crevice and it mainly consists of substances derived from serum, leukocytes, bacteria, activated epithelial cells, connective tissue cells, and bone cells as these possess a great potential for serving as indicators of periodontal disease and healing after therapy. It plays a special part in maintaining the structure of junctional epithelium and the antimicrobial defense of periodontium. Some of the suspected periodontal pathogens such as Porphyromonas gingivalis and Treponema denticola produce broad-spectrum neutral proteinases as part of their virulence arsenal. Present review article gives a brief of every aspect about GCF.

Keywords: Cells, Exudate, Fluid, Gingival crevicular fluid, Gingiva, Inflammation, Leukocytes, Periodontium