Nursing Protocol for Managing Rodenticide-Induced Acute Liver Failure with Low Volume Plasma Exchange

Sumathy Jayaraman, Sangeetha S, Gnanadeepam S

Abstract: Rodenticide poisoning, particularly from yellow phosphorus ingestion, remains a life-threatening condition in India due to the absence of specific antidotes and limited access to liver transplantation. Low Volume Plasma Exchange (LVPE) has emerged as a practical and effective therapeutic intervention for managing such cases, particularly in resource-constrained settings. This article presents a comprehensive clinical nursing protocol for managing rodenticide toxicity using LVPE, including patient preparation, monitoring, and post-procedure care. Emphasis is placed on the nurse?s role in early identification of complications, coordination with interdisciplinary teams, and patient education. By standardizing the nursing approach to LVPE, this protocol aims to improve patient outcomes, enhance safety, and support nurses in delivering evidence-based care for toxicological emergencies.

Keywords: low volume plasma exchange, nursing protocol, yellow phosphorus poisoning, rodenticide toxicity, Acute liver failure